Research is about to begin on CBD for Covid-19 symptoms. And I suspect that CBD will be shown to help with Covid' symptoms based on three important discoveries...
Why do some people with Covid-19 have minimal symptoms? While for others it takes their life? No doubt there are factors, including pre-existing conditions, age, and genetics.
And I'm also hearing on theory that people don't die from the virus directly, but from their immune systems' over-reaction to the virus. So one hypothesis is that it has to do with immune system resilience. I saw this Washington Post headline...
1. "Flu's Lethality Is Attributed To Immune Systems Overreacting To The Virus"
So my first discovery was about the flu, which also kills many people. The flu virus mostly takes up residence in the lungs, while Covid-19 moves into the lungs and others organs too. The similarity is that the immune system then floods those organs with inflammatory chemicals in order to fight the virus, creating increasing inflammation in those organs. And it's that inflammation that is perhaps the most damaging.
Washington Post, 2012 "The 2009 swine flu killed more than 18,000 people worldwide, according to the World Health Organization. Scientists say immune overreactions caused the majority of those fatalities.
New research about how the virus works on the cellular level has uncovered what makes influenza so deadly: It destroys its host — you — by using your body’s own defenses against itself.
“This is where the science is right now,” said Trish Perl, a senior epidemiologist at Johns Hopkins Hospital. “That’s what happens with a lot of severe infections. . . . It’s almost like the system goes into overdrive.” This, he said, combined with the lung damage cause by the influenza virus itself, leads to fatal cases of pneumonia."
The second insight is about how we might modulate that immune reaction. Which brings me to your Endocannabinoid System or ECS for short. It turns out that one of the main functions of your ECS is to keep your bodies systems working in their normal range, including your immune system. This is called Homeostasis, a very important function within your body.
2. Your Endocannabinoid System is involved with Homeostasis: keeping your bodies systems working in their normal range.
Lets listen to Dr. Jeffrey Chan, as he describes how our ECS is involved with Homeostasis, and how significant that is (skip to 2:55 if you want):
"If you had to sum up the function of the endocannabinoid system in one word, it would be homeostasis, the maintenance of a stable system despite external stressors and changes in the environment." - Dr. Jeffrey Chen, UCLA Cannabis Research
I expect that many illnesses are a result of the body losing homeostasis due to things like toxins, bacteria or viruses.
Next we look at several studies where CBD had a beneficial effect on either immune activity or viral activity.
3. Three Studies where CBD helped modulate immune activity and/or inhibited viral replication:
"Thus, we conclude that CBD administered therapeutically, i.e. during an ongoing inflammatory process, has a potent anti-inflammatory effect and also improves the lung function in mice submitted to LPS-induced ALI. Therefore the present and previous data suggest that in the future cannabidiol might become a useful therapeutic tool for the attenuation and treatment of inflammatory lung diseases."
2) Potential of Cannabidiol for the Treatment of Viral Hepatitis
"Moreover, CBD administration at the time of viral infection exerts long-lasting effects, ameliorating motor deficits in the chronic phase of the disease in conjunction with reduced microglial activation and pro-inflammatory cytokine production."
"Together, our findings highlight the anti-inflammatory effects of CBD in this viral model of MS and demonstrate the significant therapeutic potential of this compound for the treatment of pathologies with an inflammatory component."
There you have it! It looks probable to me that CBD would provide some degree of protection from developing the full symptoms of Covid-19, through its ability to help reduce viral replication and regulate inflammation, or what could be called 'fortifying homeostasis'.